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Table 7 Inhalability adjusted particle penetration (50% cut-point) through respiratory tract regions

From: Thoracic and respirable particle definitions for human health risk assessment

V daily(%-tile) Normal   Gradual  
  Augmenter Mouth-breather Augmenter Oral only
  P(ET) avg P(TB) avg P(ET) avg P(TB) avg P(ET) avg P(TB) avg P(ET) avg P(TB) avg
Male         
5% 2.92 a 2.72 4.97 4.24 3.55 3.22 8.24 6.38
95% CI (1.71–4.90) (1.64–4.26) (3.09–7.66) (2.81–5.85) (2.11–5.82) (2.00–4.85) (5.66–11.4) (4.89–7.59)
50% 2.44 2.30 4.93 4.21 3.33 3.02 7.52 5.90
95% CI (1.43–4.12) (1.37–3.67) (3.11–7.51) (2.84–5.67) (1.99–5.43) (1.87–4.54) (5.12–10.5) (4.50–6.98)
95% 2.14 2.02 4.92 4.22 3.15 2.88 7.14 5.71
95% CI (1.25–3.62) (1.20–3.29) (3.13–7.44) (2.87–5.64) (1.89–5.15) (1.78–4.36) (4.84–10.1) (4.32–6.77)
Female         
5% 2.90 2.70 4.22 3.72 3.08 2.85 8.06 6.23
95% CI (1.70–4.87) (1.63–4.20) (2.56–6.73) (2.38–5.34) (1.81–5.13) (1.73–4.40) (5.53–11.2) (4.78–7.41)
50% 2.41 2.26 4.36 3.81 2.89 2.67 7.35 5.77
95% CI (1.41–4.06) (1.35–3.60) (2.70–6.80) (2.50–5.29) (1.71–4.79) (1.63–4.12) (5.00–10.3) (4.39–6.83)
95% 2.10 1.99 4.46 3.89 2.72 2.52 7.00 5.60
95% CI (1.23–3.55) (1.18–3.23) (2.80–6.87) (2.58–5.33) (1.61–4.42) (1.53–3.93) (4.74–9.91) (4.22–6.66)
Child-B b         
5% 2.76 2.60 4.22 3.73 4.21 3.72 7.73 6.20
95% CI (1.62–4.64) (1.56–4.11) (2.56–6.69) (2.39–5.38) (2.56–6.68) (2.39–5.37) (5.28–10.8) (4.65–7.52)
50% 2.24 2.13 4.27 3.75 3.99 3.54 7.05 5.63
95% CI (1.31–3.79) (1.27–3.44) (2.65–6.66) (2.46–5.20) (2.45–6.30) (2.28–5.01) (4.77–9.98) (4.25–6.74)
95% 1.89 1.80 4.25 3.71 3.91 3.45 6.56 5.21
95% CI (1.10–3.21) (1.07–2.96) (2.67–6.56) (2.47–4.99) (2.42–6.12) (2.25–4.78) (4.42–9.37) (3.96–6.15)
Child-A c         
5% 3.87 3.52 5.40 4.62 5.39 4.61 7.73 6.20
95% CI (2.28–6.36) (2.17–5.27) (3.34–8.32) (3.07–6.32) (3.34–8.31) (3.06–6.31) (5.28–10.8) (4.65–7.52)
50% 3.15 2.92 5.20 4.44 4.96 4.28 7.05 5.63
95% CI (1.85–5.29) (1.77–4.49) (3.26–7.96) (3.00–5.88) (3.09–7.66) (2.86–5.75) (4.77–9.98) (4.25–6.74)
95% 2.66 2.49 5.00 4.26 4.73 4.07 6.56 5.21
95% CI (1.56–4.47) (1.50–3.91) (3.16–7.64) (2.92–5.51) (2.96–7.29) (2.74–5.39) (4.42–9.37) (3.96–6.15)
  1. P(ET)avg, extrathoracic particle penetration which is the thoracic particle fraction averaged across all activity levels weighted by daily ventilation; P(TB)avg, tracheobronchial particle penetration which is the respirable particle fraction averaged across all activity levels weighted by daily ventilation; 95% CI, ninety-five percent confidence intervals for inter-individual variability attributable to differences in particle penetration through the extrathoracic region; a Aerodynamic particle diameter in μm; b Scaling factor in Equations 2 and 3 equal to 1.26; c Scaling factor in Equations 2 and 3 equal to 1.0.