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Table 3 Associations of mitochondrial DNA methylation with exposure levels of airborne pollutants

From: Effects of airborne pollutants on mitochondrial DNA Methylation

Marker

β *

SD*

p-value*

 

Study 1 – Association with metal-rich particulate matter (PM 1 )

MT-TF & MT-RNR1

1.35

0.33

0.025

D-loop

−0.02

0.17

0.96

 

Study 2 – Association with airborne benzene

MT-TF & MT-RNR1

−0.37

0.08

0.18

D-loop

−0.03

0.08

0.91

 

Study 3 – Association with traffic-derived elemental carbon

MT-TF & MT-RNR1

−0.18

0.51

0.64

D-loop

0.56

0.85

0.37

  1. *Adjusted for age and smoking status. Exposure variables were log-transformed to improve model fit.
  2. † Regression coefficient estimating the difference in mitochondrial DNA methylation (%) associated with an increase in exposure levels from the 90th to the10th percentile.