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Table 3 Associations of mitochondrial DNA methylation with exposure levels of airborne pollutants

From: Effects of airborne pollutants on mitochondrial DNA Methylation

Marker β * SD* p-value*
  Study 1 – Association with metal-rich particulate matter (PM 1 )
MT-TF & MT-RNR1 1.35 0.33 0.025
D-loop −0.02 0.17 0.96
  Study 2 – Association with airborne benzene
MT-TF & MT-RNR1 −0.37 0.08 0.18
D-loop −0.03 0.08 0.91
  Study 3 – Association with traffic-derived elemental carbon
MT-TF & MT-RNR1 −0.18 0.51 0.64
D-loop 0.56 0.85 0.37
  1. *Adjusted for age and smoking status. Exposure variables were log-transformed to improve model fit.
  2. † Regression coefficient estimating the difference in mitochondrial DNA methylation (%) associated with an increase in exposure levels from the 90th to the10th percentile.