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Table 5 Calculated AuNP deposition density on the alveolar epithelium

From: Cellular uptake and localization of inhaled gold nanoparticles in lungs of mice with chronic obstructive pulmonary disease

Parameter Value
CMD of Au NP (nm) 21
Volume of AuNP (cm3 ), calculated median volume of spherical AuNP with density given below 4.9 × 10-18
Nominal density of Au (g/cm 3 ) 19.3
Mass of AuNP (g), calculated from data above 9.4 × 10-17
AuNP aerosol mass concentration (mg/m3 ), calculated from data in Table  4 and Table  5 1.20
Number of AuNP deposited in lungs, 120 min, calculated from data in Table  4 and Table  5 1.3 × 1010
AuNP deposited mass, 120 min (g) calculated from data in Table  4 and Table  5 1.24 × 10-6
Total projected area of all AuNP deposited (cm2 ) calculated from data above 2.2 × 10-10
Lung surface area (cm2 ), [25] 400
Fraction of NP coverage of lung surface (cm2 ) calculated from data above 5.5 × 10-13
Mean linear distance between 2 NP (nm), [25] 7.4
  1. CMD, count median diameter.