Skip to main content

Table 11 Dosimetry and calculated surface and volume lung burden

From: Comparative inhalation toxicity of multi-wall carbon nanotubes, graphene, graphite nanoplatelets and low surface carbon black

 

MWCNT

Graphene

Graphite nanoplatelets

Carbon black

Highest target concentration [mg/m3]

2.5

10

10

10

Hg surface area [m2/g]

161

131

74

32

Apparent density [g/mL]

0.15

0.04

0.02

0.52

Calculated deposition using apparent density [mg/lung]*

0.03

0.26

0.20

0.10

Calculated volumetric lung burden using apparent density [μL/lung]**

0.19

4.79

3.67

0.50

Agglomerate density [g/mL]

0.39

0.29

0.89

1.05

Calculated deposition using agglomerate density [mg/lung]*

0.03

0.30

0.11

0.33

Calculated volumetric lung burden using agglomerate density [μL/lung]**

0.07

1.02

0.52

0.31

Calculated surface lung burden using agglomerate density [m2/lung]

0.005

0.039

0.008

0.010

Pulmonary response

+++

+

(−)

-

  1. * Calculated with Multiple-Path Particle Dosimetry Model (MPPD v 2.11).
  2. ** Based on calculated disposition data.