Figure 2

Fold change RNA of BEAS-2B cells for IL-8 (A) and HOX1 (B) following exposure to 250 μg NIST 1648. There were significant increases in RNA after exposure of submerged cells only. In contrast, no increased RNA was observed following exposure of BEAS-2B cells grown at ALI to the same particle. *Significant increase relative to RNA in unexposed BEAS-2B cells.