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Figure 5 | Particle and Fibre Toxicology

Figure 5

From: Growth of human bronchial epithelial cells at an air-liquid interface alters the response to particle exposure

Figure 5

Fold change RNA of NHBE cells grown in 95% air-5% CO 2 (normoxia) and 95% N 2 -5% CO 2 (hypoxia) for 24 hours and exposed to 250 μg NIST 1648 in 25 μL for 4 hr. The change in RNA for normoxic and hypoxic cells are provided relative to unexposed normoxic and hypoxic cells respectively. While IL-8 and HOX1 RNA was significantly elevated after particle exposure, fold change RNA after hypoxia was significantly increased relative to normoxia. *Significant difference relative to exposed normoxia.

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