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Figure 7 | Particle and Fibre Toxicology

Figure 7

From: Engineered silica nanoparticles act as adjuvants to enhance allergic airway disease in mice

Figure 7

Heat map of gene expression array. Gene expression in lung tissue was analyzed with a 96-gene array. Relative increased gene expression towards control is indicated in red (≥2 fold expression) and relative decreased gene expression in green (≤2 fold). Black labels indicate no differences in gene expression. Increased gene expression in allergic and SNP exposed animals was found for various cytokines, chemokines and immune responsive genes as well as secretory mucus/surfactant genes. No changes greater than 2-fold were found for oxidative stress response, growth factors and different transcription factors (Additional file 1: Figure S5).

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