Figure 10

Intracellular fate of GO nanoplatelets. A) GO nanoplatelet freely localized (black arrow) in the cytoplasm. B) Degraded mitochondria (mt #). C) Interaction of a GO nanoplatelet (black arrow) with a lysosome (ly). For comparative purposes extracellular GO nanoplatelets are highlighted (black arrows). D) Interaction of cytosolic GO nanoplatelets with a mitochondrion (mt). E) Intracellular aggregation of GO nanoplatelets (black arrows with asterisks). F) High-magnification image of the boxed-in area in E showing a vesicle with GO nanoplatelet aggregates and degraded cell organelles. GO nanoplatelets (inside and outside the cell) are exemplarily indicated with black arrows. G) Phagosome-like vesicle with aggregates of GO nanoplatelets (arrow with asterisk) in close proximity to mitochondria (mt). H) High-magnification image (250000X) of the boxed-in area in G showing the laminar nature of the enclosed material (black arrow). Scale bars are 200 nm in A, 500 nm in B, C, D and F, 2 μm in E and G, and 100 nm in H.