Figure 11

Intracellular fate of CXYG nanoplatelets. Images A, B, C and D show SEM micrographs of an intracellular CXYG nanoplatelets aggregation (black arrow with asterisk) at different magnifications (50 k, 250 k, 300 k and 400 k X, respectively). The boxed-in areas indicate the part of the image that was amplified in the image of next higher magnification, respectively. Image E shows the interaction of an intracellular CXYG aggregation (black asterisk) with a vacuole (v). The site of interaction between the two compartments is represented at higher magnification in F. Image G shows two intracellular CXYG aggregates (black asterisk) in close proximity to each other and surrounded by intermediate filament bundles (if). H shows the ultrastructure of a cell exposed to CXYG for 72 h. The black asterisk indicates the site of CXYG accumulation. The scale bar displayed in A and H corresponds to 2 μm. The scale bars in B and H are 500 nm. The scale bars represented in C and D correspond to 100 nm. The scale bar in E and G is 1 μm. Other cellular structures indicated in Figure 11 are indicated as followed: pm: plasma membrane, nc: nucleus, mt: mitochondrion, lp: lipid, v: intracellular vacuole.