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Figure 4 | Particle and Fibre Toxicology

Figure 4

From: Internalization and cytotoxicity of graphene oxide and carboxyl graphene nanoplatelets in the human hepatocellular carcinoma cell line Hep G2

Figure 4

Effect of GO and CXYG on Hep G2 cell viability. Hep G2 cells were exposed to increasing concentrations of GO (grey bars) or CXYG (dark grey bars) for 72 h. GO and CXYG suspensions were prepared by diluting aqueous stock suspensions in medium supplemented with 10% FBS. The vehicle control (VC) consisted of 10% (v/v) Milli-Q water in medium. Cells incubated with only medium served as negative control (NC) (black bars). Cytotoxicity of GO and CXYG was assessed by means of the alamarBlue assay (A), CFDA-AM assay (B), NRU assay (C) and the fluorescamine assay (D). Bars represent the mean and standard error of the mean (SEM) of at least three independent repetitions. Statistically significant differences with respect to the vehicle control (one-way rmANOVA, Dunnett´s Post-hoc test) are indicated as followed: ☆ p < 0.05, ☆☆ p < 0.01.

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