TY - JOUR AU - Wang, Pingli AU - You, Dahui AU - Saravia, Jordy AU - Shen, Huahao AU - Cormier, Stephania A. PY - 2013 DA - 2013/07/16 TI - Maternal exposure to combustion generated PM inhibits pulmonary Th1 maturation and concomitantly enhances postnatal asthma development in offspring JO - Particle and Fibre Toxicology SP - 29 VL - 10 IS - 1 AB - Epidemiological studies suggest that maternal exposure to environmental hazards, such as particulate matter, is associated with increased incidence of asthma in childhood. We hypothesized that maternal exposure to combustion derived ultrafine particles containing persistent free radicals (MCP230) disrupts the development of the infant immune system and results in aberrant immune responses to allergens and enhances asthma severity. SN - 1743-8977 UR - https://doi.org/10.1186/1743-8977-10-29 DO - 10.1186/1743-8977-10-29 ID - Wang2013 ER -