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Table 1 Cytokines and chemokines in BALF (pg/ml)

From: Maternal exposure to combustion generated PM inhibits pulmonary Th1 maturation and concomitantly enhances postnatal asthma development in offspring

 

NS/NS

MCP230/NS

NS/OVA

MCP230/OVA

IFN-γ

11.17 ± 5.26

6.69 ± 2.00

12.77 ± 1.08

10.73 ± 2.75

IL-4

N.D.

N.D.

9.22 ± 1.26

18.62 ± 3.48 #

IL-5

N.D.

N.D.

28.09 ± 10.96

38.59 ± 16.26 #

IL-13

5.69 ± 1.79

2.46 ± 0.98

12.36 ± 2.85*

20.91 ± 4.27*

IL-10

3.27 ± 0.74

1.63 ± 0.30

2.89 ± 0.28

4.08 ± 0.46*

RANTES

N.D.

N.D.

1.46 ± 0.12

2.19 ± 0.20 #

MCP-1

N.D.

N.D.

23.03 ± 4.84

26.08 ± 7.66

KC

9.82 ± 0.68

9.24 ± 0.28

16.00 ± 1.48*

15.11 ± 1.02*

  1. Cytokines and chemokines in BALF were examined using a Milliplex mouse cytokine/chemokine assay kit. Results are expressed as means ± SEM. n = 7-8 mice/group. #p < 0.05 MCP230/OVA vs. NS/OVA; *p < 0.05 NS/OVA vs. NS/NS, MCP230/OVA vs. MCP230/NS; N.D.: non-detected.
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Particle and Fibre Toxicology

ISSN: 1743-8977

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