| |
NS/NS
|
MCP230/NS
|
NS/OVA
|
MCP230/OVA
|
|---|
|
IFN-γ
|
11.17 ± 5.26
|
6.69 ± 2.00
|
12.77 ± 1.08
|
10.73 ± 2.75
|
|
IL-4
|
N.D.
|
N.D.
|
9.22 ± 1.26
|
18.62 ± 3.48 #
|
|
IL-5
|
N.D.
|
N.D.
|
28.09 ± 10.96
|
38.59 ± 16.26 #
|
|
IL-13
|
5.69 ± 1.79
|
2.46 ± 0.98
|
12.36 ± 2.85*
|
20.91 ± 4.27*
|
|
IL-10
|
3.27 ± 0.74
|
1.63 ± 0.30
|
2.89 ± 0.28
|
4.08 ± 0.46*
|
|
RANTES
|
N.D.
|
N.D.
|
1.46 ± 0.12
|
2.19 ± 0.20 #
|
|
MCP-1
|
N.D.
|
N.D.
|
23.03 ± 4.84
|
26.08 ± 7.66
|
|
KC
|
9.82 ± 0.68
|
9.24 ± 0.28
|
16.00 ± 1.48*
|
15.11 ± 1.02*
|
- Cytokines and chemokines in BALF were examined using a Milliplex mouse cytokine/chemokine assay kit. Results are expressed as means ± SEM. n = 7-8 mice/group. #p < 0.05 MCP230/OVA vs. NS/OVA; *p < 0.05 NS/OVA vs. NS/NS, MCP230/OVA vs. MCP230/NS; N.D.: non-detected.
