Skip to main content

Table 4 Summary of PFP induced antioxidant expression

From: Combustion-derived flame generated ultrafine soot generates reactive oxygen species and activates Nrf2 antioxidants differently in neonatal and adult rat lungs

  Assay Lung compartment Neonates Adults
HMOX1 RT-PCR Airway NC NC
  Parenchyma + +
WB Whole Lung NC +
IHC Airway + +
  Parenchyma NC +
SOD1 RT-PCR Airway NC +
  Parenchyma - NC
WB Whole Lung NC +
IHC Airway NC +
  Parenchyma NC +
SOD2 RT-PCR Airway NC NC
  Parenchyma NC -
WB Whole Lung NC NC
IHC Airway NC NC
  Parenchyma NC NC
CAT RT-PCR Airway NC NC
  Parenchyma NC -
WB Whole Lung NC NC
IHC Airway NC +
  Parenchyma NC +
PRDX6 RT-PCR Airway NC NC
  Parenchyma + NC
WB Whole Lung NC NC
IHC Airway NC NC
   Parenchyma NC NC