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Table 2 Mean residence time (MRT) of silver after 28 days of oral administration

From: Biopersistence of silver nanoparticles in tissues from Sprague–Dawley rats

Tissue Male Female
  100 mg/kg/day 500 mg/kg/day 100 mg/kg/day 500 mg/kg/day
  (days) (days) (days) (days)
A. 10 nm
Blood 2.85 10.02 4.70 11.24
Brain 58.60 54.44 57.82 53.54
Kidneys 31.03 49.12 42.10 49.60
Liver 21.49 32.05 48.77 29.82
Spleen 38.24 43.43 39.52 43.58
Testes/Ovaries 55.32 63.68 44.70 44.19
B. 25 nm
Blood 3.75 6.47 5.53 11.25
Brain 55.06 52.43 58.57 56.93
Kidneys 25.80 34.67 34.33 46.72
Liver 22.40 29.99 33.89 37.42
Spleen 30.75 40.95 48.11 35.81
Testes/Ovaries 55.34 63.31 48.29 41.75