Kinetic parameters | Unit | Cd | Te |
---|
Vd | ml/kg | 110.48 ± 1.36 | 115.91 ± 2.44 |
AUC | μg · h /ml | 2.16 ± 0.07**
| 0.99 ± 0.13 |
CL | ml/h/kg | 10.40 ± 0.48*
| 8.99 ± 1.53 |
t
1/2α
| h | 0.14 ± 0.06 | 0.13 ± 0.03 |
t
1/2β
| h | 12.41 ± 0.26*
| 14.40 ± 1.33 |
- Vd, apparent volume of distribution, AUC, area under the blood concentration-time profiles, CL, clearance t
1/2α
, distribution half-life, t
1/2β
, elimination half-life.
- Kinetic parameters (AUC, CL and t
1/2β
) of Cd were significantly different compared with those of Te in the blood, *
p < 0.05, **
p < 0.01.
- All data are represented as the mean ± SD, n = 6.