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Table 3 Kinetic parameters of Cd and Te in mice exposed to CdTe/ZnS aqQDs

From: Degradation of aqueous synthesized CdTe/ZnS quantum dots in mice: differential blood kinetics and biodistribution of cadmium and tellurium

Kinetic parameters

Unit

Cd

Te

Vd

ml/kg

110.48 ± 1.36

115.91 ± 2.44

AUC

μg · h /ml

2.16 ± 0.07**

0.99 ± 0.13

CL

ml/h/kg

10.40 ± 0.48*

8.99 ± 1.53

t 1/2α

h

0.14 ± 0.06

0.13 ± 0.03

t 1/2β

h

12.41 ± 0.26*

14.40 ± 1.33

  1. Vd, apparent volume of distribution, AUC, area under the blood concentration-time profiles, CL, clearance t 1/2α , distribution half-life, t 1/2β , elimination half-life.
  2. Kinetic parameters (AUC, CL and t 1/2β ) of Cd were significantly different compared with those of Te in the blood, * p < 0.05, ** p < 0.01.
  3. All data are represented as the mean ± SD, n = 6.