Figure 1

FESEM examples of MWCNT in lung and kidney tissue sections after MWCNT inhalation exposure. FESEM image of alveolar macrophages 1 day post-exposure in Figure 1 A shows typical examples of MWCNT fibers protruding from the surface of alveolar macrophages (black arrow multiple fibers, white arrows singlets). Examples of MWCNT found in the alveolar interstitial space are shown in Figure 1 B (336 day post-exposure). The image of a kidney section in Figure 1 C shows a typical example of the single MWCNT found in extrapulmonary organs (336 day post-exposure). The location of this MWCNT singlet within Bowman’s capsule of the kidney is shown by the black rectangle given in the low magnification insert in the lower left of the figure.