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Figure 1 | Particle and Fibre Toxicology

Figure 1

From: Bioenergetic failure correlates with autophagy and apoptosis in rat liver following silver nanoparticle intraperitoneal administration

Figure 1

Characterization of Ag-nps. Size distribution of Ag-nps following dispersion in water (A-B) and their distribution in suborganelles of liver tissues obtained from rats at day 30 following Ag-nps administration (C). Tissues were processed for TEM evaluation as described under Materials and Methods. Accelerating voltages and magnifications were indicated at right lower corner. A-B: particle size distribution evaluated from the corresponding TEM micrograph (n = 109). C: scale bars size represent 0.5 μm in panels 1 and 6, 0.1 μm in panel 2, 1 μm in panel 3, 0.2 μm in panel 4, and 2 μm in panel 5. Panel 2 represents the enlargement of white square area indicated in panel 1. Panel 4 and 6 represents the enlargement of white square area indicated in panel 3 and 5, respectively. White dotted lines in panel 2 indicate diameters of Ag-nps. White arrow in panel 4 indicates endosome. Black arrow in panel 6 indicates lysosome.

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