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Figure 2 | Particle and Fibre Toxicology

Figure 2

From: Predictive value of in vitro assays depends on the mechanism of toxicity of metal oxide nanoparticles

Figure 2

Cytotoxicity and IL-8 expression of 16-HBE cells after exposure to NPs for 24 h. (A) Cytotoxicity was measured by trypan blue exclusion for ZnO and CuO NP whilst others were measured by LDH. (B) Levels of IL-8 of 16-HBE cells at 24 h following treatment. Note that the surface area doses were 30, 100, and 300 cm2/mL except for ZnO and CuO NP which were 3, 10, and 30 cm2/mL. Values are mean ± SD from minimum four independent experiments. Significance versus vehicle control (VEH): * p < 0.05, *** p < 0.001.

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