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Figure 10 | Particle and Fibre Toxicology

Figure 10

From: Effect of MWCNT size, carboxylation, and purification on in vitro and in vivo toxicity, inflammation and lung pathology

Figure 10

Example of how MWCNT retention is determined in an unstained lung section. A) Low resolution digitized image, composed of auto-fluorescence (tissue) and light loss (MWCNT), of lung section from N/S-O MWCNT-exposed mouse. Blue box indicates the scanning area. B) High resolution digitized image, composed of auto-fluorescence (tissue) and light loss (MWCNT), of scanning area from Figure 10A. C) Gated scatter-gram with total scan areas collected where the purple area indicates positive phantom contours for particle deposition. D) Low resolution digitized image, composed of auto-fluorescence (tissue) and light loss (MWCNT), of lung section from N/L-O MWCNT-exposed mouse. Blue box indicates the scanning area. E) High resolution digitized image, composed of auto-fluorescence (tissue) and light loss (MWCNT), of scanning area from Figure 10C. F) Gated scatter-gram with total scan areas collected where the purple area indicates positive phantom contours for particle deposition.

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