Figure 7

Ex vivo cytokine release from cells recovered in lung lavage at 24 hours post MWCNT instillation. A) IL-6 release from lavaged cells without LPS co-culture. B) TNF-α release from lavaged cells without LPS co-culture. C) IL-1β release from lavaged cells with LPS co-culture (20 ng/ml). Asterisks indicate significance *** at P < 0.001, ** at P < 0.01, * at P < 0.05 compared to Vehicle. Dagger indicates significance † at P < 0.05 compared to the original narrow/short MWCNT variant. n = 3 mice per condition.