From: Low-solubility particles and a Trojan-horse type mechanism of toxicity: the case of cobalt oxide on human lung cells
Analytical technique
Exposure compound
Intracellular solubilized Co
Mean ± SD (fg/cell)
PIXE
Co3O4
6.7 ± 3.0
nucleus : 3.3 ± 2.0
cytoplasm: 3.4 ± 1.5
ICP-MS
6.5 ± 2.0
CoCl2
5.4 ± 0.8