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Table 4 Summary of the results obtained for the intracellular quantification and distribution of solubilized cobalt after exposure of BEAS-2B cells for 72 h to Co 3 O 4 particles and soluble CoCl 2 (both at IC25)

From: Low-solubility particles and a Trojan-horse type mechanism of toxicity: the case of cobalt oxide on human lung cells

Analytical technique Exposure compound Intracellular solubilized Co
Mean ± SD (fg/cell)
PIXE Co3O4 6.7 ± 3.0
nucleus : 3.3 ± 2.0
cytoplasm: 3.4 ± 1.5
ICP-MS Co3O4 6.5 ± 2.0
PIXE CoCl2 5.4 ± 0.8