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Table 4 Blood parameters in shams and mice after sub-acute exposure to ZnO NPs

From: Toxicity assessment of zinc oxide nanoparticles using sub-acute and sub-chronic murine inhalation models

Sub-acute study Experimental group:
Whole blood parameter Shams ZnO 0 wk ZnO 3 wks
WBC × 103/μL 2.91 ± 0.9 2.81 ± 0.3 3.11 ± 0.4
RBC × 106/μL 9.85 ± 0.3 10.27 ± 0.5 9.49 ± 0.2
Hemoglobin, g/dL 16.5 ± 0.4 17.3 ± 0.6 15.3 ± 0.2
Hematocrit,% 47.7 ± 1.3 51.3 ± 2.0 52.7 ± 1.1**
Monocytes × 103/μL 0.33 ± 0.1 0.33 ± 0.0 0.39 ± 0.1
Neutrophils × 103/μL 0.56 ± 0.1 0.38 ± 0.1 0.84 ± 0.1
Lymphocytes × 103/μL 1.95 ± 0.7 2.02 ± 0.3 1.83 ± 0.3
Eosinophils × 103/μL 0.052 ± 0.016 0.052 ± 0.016 0.082 ± 0.019
Basophils × 103/μL 0.014 ± 0.008 0.022 ± 0.009 0.018 ± 0.007
  1. Values are expressed as mean and SE, WBC - white blood cells, RBC - red blood cells; **p < 0.02 (significantly different from shams), n = 6 in each group.