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Table 4 Blood parameters in shams and mice after sub-acute exposure to ZnO NPs

From: Toxicity assessment of zinc oxide nanoparticles using sub-acute and sub-chronic murine inhalation models

Sub-acute study

Experimental group:

Whole blood parameter

Shams

ZnO 0 wk

ZnO 3 wks

WBC Ă— 103/ÎĽL

2.91 ± 0.9

2.81 ± 0.3

3.11 ± 0.4

RBC Ă— 106/ÎĽL

9.85 ± 0.3

10.27 ± 0.5

9.49 ± 0.2

Hemoglobin, g/dL

16.5 ± 0.4

17.3 ± 0.6

15.3 ± 0.2

Hematocrit,%

47.7 ± 1.3

51.3 ± 2.0

52.7 ± 1.1**

Monocytes Ă— 103/ÎĽL

0.33 ± 0.1

0.33 ± 0.0

0.39 ± 0.1

Neutrophils Ă— 103/ÎĽL

0.56 ± 0.1

0.38 ± 0.1

0.84 ± 0.1

Lymphocytes Ă— 103/ÎĽL

1.95 ± 0.7

2.02 ± 0.3

1.83 ± 0.3

Eosinophils Ă— 103/ÎĽL

0.052 ± 0.016

0.052 ± 0.016

0.082 ± 0.019

Basophils Ă— 103/ÎĽL

0.014 ± 0.008

0.022 ± 0.009

0.018 ± 0.007

  1. Values are expressed as mean and SE, WBC - white blood cells, RBC - red blood cells; **p < 0.02 (significantly different from shams), n = 6 in each group.