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Figure 8 | Particle and Fibre Toxicology

Figure 8

From: In vitro determinants of asbestos fiber toxicity: effect on the relative toxicity of Libby amphibole in primary human airway epithelial cells

Figure 8

A cellular determination of surface iron concentrations and corresponding reactive oxygen species generation by each of the asbestos mineral types. (A) Ionizable iron concentrations measured by ICP-OES following treatment of the samples with 3.0 N HCl (B) Surface chelatable iron concentrations measured by ICP-OES following treatment of the samples with citrate-bicarbonate-dithionite (CBD) (C) Spectrophotometric assay measuring the thiobarbituric acid-reactive products of deoxyribose as a measure of hydroxyl radical production. Significant difference between the LA and amosite samples are denoted with (*). Significant difference between the two LA samples or between the two amosite samples denoted with (#). Differences are considered significant if p < 0.05.

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