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Table 1 Characterization of amphibole samples

From: In vitro determinants of asbestos fiber toxicity: effect on the relative toxicity of Libby amphibole in primary human airway epithelial cells

 

LA2000

LA2007

RTI amosite

UICC amosite

Particle count

    

N (Total Particles)

561

510

588

525

N (EMP)a

450

250

292

178

Particle number /mg

    

Total particles x107 /mg

98.2

103

9.15

94.2

EMP a x107 /mg

78.7

50.5

4.5

31.9

Particle size distribution

    

Total particle mean length (μm)

3.7 ± 0.2

2.3 ± 0.2

6.4 ± 0.6

2.1 ± 0.3

Total particle mean width (μm)

0.36 ± 0.02

0.36 ± 0.01

0.44 ± 0.01

0.43 ± 0.01

Total particle mean aspect ratio

12.8 ± 0.6

8.4 ± 0.7

16.9 ± 1.6

5.6 ± 0.6

EMP a mean length (μm)

4.4 ± 0.2

3.8 ± 0.3

12.1 ± 1.2

4.3 ± 0.5

EMP a mean width (μm)

0.30 ± 0.01

0.29 ± 0.02

0.37 ± 0.01

0.27 ± 0.01

EMP a mean aspect ratio

15.5 ± 0.6

15.1 ± 1.2

32.4 ± 3.0

13.0 ± 1.0

Surface area

    

Total surface area by GA (m2/g)b

5.3

7.4

3.1

4.8

EMP a surface area by TEM (m2/g)c

1.1

2.6

2.8

1.5

Sum of particle length

    

∑ (All particle lengths) x106 (μm/μg)

1.02

2.89

2.15

1.68

∑ ( EMP a lengths) x106 (μm/μg )

0.97

2.39

2.03

1.20

  1. a Elongated mineral particle (EMP) defined as having aspect ratio ≥ 3:1.
  2. b Measured by Kr gas adsorption (GA) and BET analysis.
  3. c Measured by TEM and calculated using the equation SA = [L*W + L*T + W*T]/[L*W*T*ρ] – See Methods section for detailed description.