Skip to main content
Figure 6 | Particle and Fibre Toxicology

Figure 6

From: Induction of stem-like cells with malignant properties by chronic exposure of human lung epithelial cells to single-walled carbon nanotubes

Figure 6

Expression of stem cell markers in CSC-like cells derived from SWCNT-exposed lung epithelial cells. (A) Analysis of pluripotent stem cell markers in SP and non-SP (NSP) derived from malignant transformed BSW cells using the Proteome Profiler™ Array (R&D Systems). Pixel densities of remarkable stem cell markers (1) Nanog, (2) SOX-2, (3) E-cadherin (E-Cad), and (4) SOX-17 from the arrays are shown. (B) Western blot analysis of Nanog, SOX-2, E-cadherin, and SOX-17 comparing SP and NSP cells derived from BSW cells. (C, D) Analysis of stem cell surface markers CD24, CD44, and CD133 in SP and NSP cells derived from BSW cells using flow cytometry, comparing with the passage control BC cells. Plots are relative fluorescence level normalized to control BC cells. Data are means ± SD (n = 3). * p < 0.05 vs. SP cells, #p < 0.05 vs. BC cells.

Back to article page