Skip to main content

Table 2 Histological analysis of lung tissue in control and welder patients

From: Role of metal oxide nanoparticles in histopathological changes observed in the lung of welders

  Controls Welders P value
  (n = 21) (n = 21)  
Siderophages    
Presence (n patients) 10 17 0.024
Number (Mean semi-quantitative score ± SD)b 0.71 ± 0.90 1.57 ± 1.17 0.019
Ferruginous bodies (n patients)    
Presence (n patients) 6 16 0.002
Number (Mean semi-quantitative score ± SD)b 0.43 ± 0.81 1.81 ± 1.57 0.002
Fibrotic lesions (Number of patients)    
Peribronchiolar 16 20 ns
Perivascular 14 20 0.018
Paraseptal 8 10 ns
Alveolar 3 5 ns
Diffuse interstitial 6 5 ns
Pleural 4 2 ns
Severity of fibrosis a    
(Mean semi-quantitative score ± SD)    
Global 2.29 ± 1.59 3.91 ± 1.51 0.003
Peribronchiolar 1.10 ± 0.77 1.86 ± 0.85 0.005
Perivascular 1.05 ± 0.92 1.81 ± 0.81 0.010
Alveolar and peribronchiolar 1.57 ± 1.12 2.67 ± 1.16 0.004
Other respiratory lesions    
Bronchiolectasis 16 13 ns
Bronchiolar metaplasia 2 0 ns
Bronchiolar dysplasia 1 5 ns
Respiratory Bronchiolitis – Intertitial Lung Disease 10 10 ns
Desquamative intertitial pneumonitis 12 9 ns
Endogenous Lipoid Pneumonitis 1 3 ns
  1. ns: not significant; SD: standard deviation.
  2. aSemi-quantitative score [4 classes = 0: absent; 1: rare; 2: frequent; 3: important]. Adapted from Roggli classification [54].
  3. bSemi-quantitative score [5 classes = 0: 0/slide; 1: < 5/slide; 2: 5 to 10/slide; 3: 10 to 50/slide ; 4: > 50/slide].