From: Role of metal oxide nanoparticles in histopathological changes observed in the lung of welders
Controls | Welders | P value | |
---|---|---|---|
(n = 21) | (n = 21) | ||
Siderophages | |||
Presence (n patients) | 10 | 17 | 0.024 |
Number (Mean semi-quantitative score ± SD)b | 0.71 ± 0.90 | 1.57 ± 1.17 | 0.019 |
Ferruginous bodies (n patients) | |||
Presence (n patients) | 6 | 16 | 0.002 |
Number (Mean semi-quantitative score ± SD)b | 0.43 ± 0.81 | 1.81 ± 1.57 | 0.002 |
Fibrotic lesions (Number of patients) | |||
Peribronchiolar | 16 | 20 | ns |
Perivascular | 14 | 20 | 0.018 |
Paraseptal | 8 | 10 | ns |
Alveolar | 3 | 5 | ns |
Diffuse interstitial | 6 | 5 | ns |
Pleural | 4 | 2 | ns |
Severity of fibrosis a | |||
(Mean semi-quantitative score ± SD) | |||
Global | 2.29 ± 1.59 | 3.91 ± 1.51 | 0.003 |
Peribronchiolar | 1.10 ± 0.77 | 1.86 ± 0.85 | 0.005 |
Perivascular | 1.05 ± 0.92 | 1.81 ± 0.81 | 0.010 |
Alveolar and peribronchiolar | 1.57 ± 1.12 | 2.67 ± 1.16 | 0.004 |
Other respiratory lesions | |||
Bronchiolectasis | 16 | 13 | ns |
Bronchiolar metaplasia | 2 | 0 | ns |
Bronchiolar dysplasia | 1 | 5 | ns |
Respiratory Bronchiolitis – Intertitial Lung Disease | 10 | 10 | ns |
Desquamative intertitial pneumonitis | 12 | 9 | ns |
Endogenous Lipoid Pneumonitis | 1 | 3 | ns |