Pharmacokinetics, clearance, and biosafety of polyethylene glycol-coated hollow gold nanospheres

Table 2 Group means for both sacrifice dates and both sexes for clinical chemistry

	Parameter*	Creatinine	BUN	AST	ALT	ALK PHOS	T. Protein	Albumin	Globulin
	Unit	mg/dL	mg/dL	mg/dL	IU/L	IU/L	IU/L	g/dL	g/dL
14 days (Female)	Saline	<0.20	16.1	443	259	128	4.91	3.63	1.29
14 days (Female)	PEG-HAuNS	<0.20	14.3	515	316	136	5.18	3.59	1.58
90 days (Female)	Saline	<0.20	16.9	273	130	92	5.8	3.61	2.19
90 days (Female)	PEG-HAuNS	<0.20	16.4	406	202	84	5.88	3.75	2.13
14 days (Male)	Saline	<0.20	18	112	69	123	5.63	3.55	2.07
14 days (Male)	PEG-HAuNS	0.2	19.8	322	256	123	5.52	3.33	2.19
90 days (Male)	Saline	0.22	20.3	152	109	137	6.62	3.83	2.79
90 days (Male)	PEG-HAuNS	0.27	17.6	591	395	204	6.62	3.76	2.85
Reference ranges	Males	0-0.4	23-38	0-541	0-561	110-219	5.1-6.2	2.5-3.2	2.5-3.0
Reference ranges	Females	0-0.4	19-33	0-671	0-596	113-223	5.3-6.3	2.8-3.5	2.4-2.9

*BUN - blood urea nitrogen, AST - aspartate aminotransferase, ALT - alanine aminotransferase, ALK PHOS - alkaline phosphatase, T. protein - total protein.

ISSN: 1743-8977