Cardiopulmonary toxicity of peat wildfire particulate matter and the predictive utility of precision cut lung slices

Table 3 **Hemodynamics of perfused hearts* at the end of the control period (before ischemia)**

		n	LVDP	HR	+dP/dt_max	-dP/dt_min	Coronary flow rate
			(cm H₂O)	(bpm)	(cm H₂O/sec)	(cm H₂O/sec)	(mL/min)
ENCF-1	Coarse	5	115 ± 7	357 ± 41	4056 ± 1038	−3271 ± 448	2.2 ± 0.5
	Fine	5	102 ± 21	285 ± 68	3551 ± 750	−2527 ± 758	2.1 ± 0.3
	Ultrafine	5	105 ± 16	345 ± 50	2765 ± 321	−2720 ± 466	1.9 ± 0.4
ENCF-4	Coarse	4	107 ± 19	330 ± 34	3614 ± 572	−2720 ± 923	1.9 ± 0.2
	Fine	4	100 ± 5	306 ± 18	3447 ± 1172	−2665 ± 189	2.1 ± 0.3
	Ultrafine	4	106 ± 10	341 ± 39	3394 ± 481	−2750 ± 414	2.2 ± 0.2
Saline		4	120 ± 16	364 ± 47	4018 ± 1405	−2998 ± 559	2.2 ± 0.3

*Hearts were collected at 24 h post-exposure to ENCF-1 and ENCF-4 PM.
LVDP: left ventricular developed pressure, HR: heart rate, +dP/dt_max: maximum first derivative of change in left ventricular pressure/time, −dP/dt_min: minimum first derivative of change in left ventricular pressure/time.

ISSN: 1743-8977