Figure 4

A, B and C Lung adenoma, 20× and 40×. A. The figure is a representative pulmonary bronchio-alveolar adenoma from a male B6C3F1 mouse treated with MCA + MWCNT. The mass is composed of relatively uniform cells that compressed the surrounding lung tissue. The photo with taken with a 4x objective. The magnification bar is 200 microns. B. Figure 4B is a photomicrograph of a pulmonary bronchiolo-alveolar adenoma from a MCA + MWCNT treated mouse. The focal, moderately cellular mass involved a bronchiole. The mass was composed of relatively uniform cells that distorted and replaced alveolar architecture. The image was photographed using a 20x objective. The magnification bar is 50 microns. C. The light micrograph is a higher magnification of the H&E stained section demonstrating MWCNT (black fibers) in the tissue surrounding the bronchiolo-alveolar adenoma (arrows 1, 2 and 3). The light microscope image was taken using 100x oil immersion objective. The magnification bar is 20 microns.