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Table 1 Incidence of focal adenomatous hyperplasia, macrophage infiltration and foreign material in the lung by light microscopy

From: Promotion of lung adenocarcinoma following inhalation exposure to multi-walled carbon nanotubes

Focal alveolar adenomatous hyperplasia, macrophage infiltration and foreign material observed in MWCNT–treated mice 17 months following exposure

 

Air

MCA

MWCNT

MCA + MWCNT

Number of animals/group

56

54

49

42

Number animals with positive foreign material

0

0

49*

42*

Macrophage infiltration

3

9

32*

39*

Number animals with positive for focal adenomatous alveolar hyperpasia

7

8

14*

26*

  1. Statistical significance at *p < .0001.