From: Promotion of lung adenocarcinoma following inhalation exposure to multi-walled carbon nanotubes
Euthanasia | Early sacrifice | Terminal sacrifice | ||||||
---|---|---|---|---|---|---|---|---|
 | Air | MCA | MWCNT | MCA + MWCNT | Air | MCA | MWCNT | MCA + MWCNT |
Number of animals | 4 | 6 | 6 | 13 | 56 | 54 | 49 | 42 |
Number of Bronchiolo-alveolar adenomas | 0 | 1 | 0 | 4 | 6 | 18* | 9 | 32* |
% of mice with one or more Bronchiolo-alveolar adenoma | 0% | 17% * | 0% | 31% * | 11% | 33% * | 18% | 76% * |
Number of Bronchiolo-alveolar adenocarcinomas | 0 | 1 | 0 | 7 | 7 | 12 | 7 | 26 |
% of mice with Bronchiolo-alveolar Adenocarcinomas | 0% | 17% * | 0% | 54% * | 13% | 22% * | 14% | 62% * |
Number of mice with one or more– Bronchiolo-alveolar adenoma and/or Bronchio-alveolar adenocarcinomas | 0 | 2 | 0 | 8 | 13 | 28* | 13 | 38* |
Percent of mice with lung tumors | 0% | 33% | 0% | 62%* | 23.2% | 51.9%* | 26.5% | 90.5%* |