Skip to main content

Table 3 Incidence of lung tumors in early euthanized mice and mice 17 months after exposure

From: Promotion of lung adenocarcinoma following inhalation exposure to multi-walled carbon nanotubes

Euthanasia

Early sacrifice

Terminal sacrifice

 

Air

MCA

MWCNT

MCA + MWCNT

Air

MCA

MWCNT

MCA + MWCNT

Number of animals

4

6

6

13

56

54

49

42

Number of Bronchiolo-alveolar adenomas

0

1

0

4

6

18*

9

32*

% of mice with one or more Bronchiolo-alveolar adenoma

0%

17% *

0%

31% *

11%

33% *

18%

76% *

Number of Bronchiolo-alveolar adenocarcinomas

0

1

0

7

7

12

7

26

% of mice with Bronchiolo-alveolar Adenocarcinomas

0%

17% *

0%

54% *

13%

22% *

14%

62% *

Number of mice with one or more– Bronchiolo-alveolar adenoma and/or Bronchio-alveolar adenocarcinomas

0

2

0

8

13

28*

13

38*

Percent of mice with lung tumors

0%

33%

0%

62%*

23.2%

51.9%*

26.5%

90.5%*

  1. *Indicates statistical significance at p < .0001.