Skip to main content

Table 3 Incidence of lung tumors in early euthanized mice and mice 17 months after exposure

From: Promotion of lung adenocarcinoma following inhalation exposure to multi-walled carbon nanotubes

Euthanasia Early sacrifice Terminal sacrifice
  Air MCA MWCNT MCA + MWCNT Air MCA MWCNT MCA + MWCNT
Number of animals 4 6 6 13 56 54 49 42
Number of Bronchiolo-alveolar adenomas 0 1 0 4 6 18* 9 32*
% of mice with one or more Bronchiolo-alveolar adenoma 0% 17% * 0% 31% * 11% 33% * 18% 76% *
Number of Bronchiolo-alveolar adenocarcinomas 0 1 0 7 7 12 7 26
% of mice with Bronchiolo-alveolar Adenocarcinomas 0% 17% * 0% 54% * 13% 22% * 14% 62% *
Number of mice with one or more– Bronchiolo-alveolar adenoma and/or Bronchio-alveolar adenocarcinomas 0 2 0 8 13 28* 13 38*
Percent of mice with lung tumors 0% 33% 0% 62%* 23.2% 51.9%* 26.5% 90.5%*
  1. *Indicates statistical significance at p < .0001.