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Figure 10 | Particle and Fibre Toxicology

Figure 10

From: Tissue distribution and elimination after oral and intravenous administration of different titanium dioxide nanoparticles in rats

Figure 10

IV study: Organ distribution of Ti as percentage of administered dose on Day 90 after single and repeated IV dosing with NM-100 (A), NM-102 (B), NM-103 (C), and NM-104 (D) in female rats. (LOD: 0.05 μg/g). Left: liver, spleen and lung, Right: kidney, heart, brain, thymus, blood and ovaria. NM-100: brain (single exposure) < LOD, blood (single + repeated) < LOD. NM-102: brain + ovaries (single exposure) < LOD, blood (single + repeated) < LOD. NM-103: brain (single exposure) < LOD, blood (single + repeated): not measured. NM-104: brain (single exposure) < LOD, blood (single + repeated): not measured.

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