Figure 6
From: Sub-chronic toxicity study in rats orally exposed to nanostructured silica
Histopathological evaluation of livers from animals treated with SAS or NM-202 for 28 or 84 days. (A) The number of mononuclear inflammatory cells (given per cm2) in liver tissue after 28-, or 84-days of exposure (mean ± standard error of the mean; n = 5). (B) The number of apoptotic cells (given per cm2) in liver tissue after 28-, or 84-days of exposure (mean ± standard error of the mean; n = 5). (C) The number of slides (out of a maximum of 10 evaluated slides) in which fibrosis occurred. * Significant difference versus the control at that day.