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Table 1 Recommendations for measuring exposure during inhalation studies

From: Principles for characterizing the potential human health effects from exposure to nanomaterials: elements of a screening strategy

Metric

Measurement Recommendation

Mass – off-line

E (coupled with on-line)

Mass – on-line

E

Size distribution – off line

E

Size distribution – on line

E/D

Surface area – off line

O

Surface area – on line

O

Number – off line

N

Number – on line

E

  1. E: These measurements are considered to be essential.
  2. D: These measurements are considered to provide valuable information, but are not recommended as essential due to constraints associated with complexity, cost and availability.
  3. O: These measurements are considered to provide valuable but non-essential exposure information.
  4. N: These measurements are not considered to be of significant value to inhalation studies.
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Particle and Fibre Toxicology

ISSN: 1743-8977

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