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Figure 5 | Particle and Fibre Toxicology

Figure 5

From: Single-Walled Carbon Nanotube (SWCNT)-induced interstitial fibrosis in the lungs of rats is associated with increased levels of PDGF mRNA and the formation of unique intercellular carbon structures that bridge alveolar macrophages In Situ

Figure 5

Cell proliferation at (A) day 1 and (B) day 21 post-exposure in the lungs of mice exposed by oropharyngeal aspiration to saline vehicle containing 0.1% Pluronic F-68, carbon black (CB), single-walled carbon nanotubes (SWCNT) or vanadium pentoxide (V2O5). Open bars represent the labeling index in the alveolar region of the lung (open bars) and solid bars represent the labeling index in the bronchus-associated lymphatic tissue. Labelling indices were measured as described in Methods and are reported as the percentage of BrdU-labeled cells of the cells counted (minimum of 400 cells counted). *P < 0.05 compared to saline control.

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