Figure 9From: Pulmonary toxicity screening studies in male rats with TiO2 particulates substantially encapsulated with pyrogenically deposited, amorphous silicaHigher magnification light micrograph of lung tissue from a rat exposed to quartz particles (5 mg/kg) at 3 months post-instillation exposure. Note the tissue accumulation of foamy multinucleated alveolar macrophages (arrows) within alveolar spaces. This is a common feature of the progressive nature of silica induced lung disease. Magnification = ×200.Back to article page