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Figure 9 | Particle and Fibre Toxicology

Figure 9

From: Pulmonary toxicity screening studies in male rats with TiO2 particulates substantially encapsulated with pyrogenically deposited, amorphous silica

Figure 9

Higher magnification light micrograph of lung tissue from a rat exposed to quartz particles (5 mg/kg) at 3 months post-instillation exposure. Note the tissue accumulation of foamy multinucleated alveolar macrophages (arrows) within alveolar spaces. This is a common feature of the progressive nature of silica induced lung disease. Magnification = ×200.

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