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Table 2 Expression of cytokines in the lung tissue from C57xCBA mice exposed to 80 mg/m3 SRM2975

From: Cytokine expression in mice exposed to diesel exhaust particles by inhalation. Role of tumor necrosis factor

Exposure

Air

DEP

Marker

 

1–6 h

1 day

Tnf

49 ± 19

46 ± 14

149 ± 82**

Il-6

0.47 ± 0.25

5.6 ± 8.1**

2.1 ± 0.52**

Mcp-1

5.3 ± 1.9

18 ± 9.6**

16 ± 11*

Mip-2

23 ± 16

43 ± 37

105 ± 38**

Kc

3.5 ± 2.4

9.4 ± 6.7*

25 ± 18**

  1. Expression of mRNA is normalized to 18S rRNA and is multiplied by 107. Mean ± S.D. is shown (n = 6–11).
  2. *P < 0.05 versus air-exposed mice.
  3. **P < 0.01 versus air-exposed mice.
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Particle and Fibre Toxicology

ISSN: 1743-8977

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