Table 4 Summary of histological lung changes due to 2-day filtered air control or exposure to concentrated ambient particulate matter
| Â | uCAP (Site I) | u+fCAP (Site II) | ||
|---|---|---|---|---|
Parameter | Control (n = 40) | CAP (n = 40) | Control (n = 64) | CAP (n = 64) |
Alveolar macrophages | Â | Â | Â | Â |
   minimal | 29 | 33 | 33 | 41 |
   slight | 0 | 3 | 2 | 2 |
Foci thick septa + macrophages | Â | Â | Â | Â |
   minimal | 22 | 23 | 31 | 28 |
   slight | 2 | 0 | 2 | 5 |
Perivascular infiltrate | 29 | 22 | 51 | 58 |
Foci interstitial pneumonia with alveolitis (macrophages + lymphocytes) | Â | Â | Â | Â |
minimal | 0 | 0 | 1 | 0 |
Peribronchitis+hypertrophy bronchial epithelium | 0 | 0 | 0 | 1 |
Macrophages loaded with Particulate matter | 0 | 0 | 0 | 52 |
Erythrocytes in alveoli | 28 | 24 | 41 | 39 |
BrdU score number examined | 40 | 39 | 64 | 64 |
   Minimal | 27 | 28 | 39 | 35 |
   Slight | 1 | 0 | 5 | 4 |