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Table 4 Results of bacterial gene point mutation assay. Cerium oxide – non-nanoparticulate. Summary of mean revertant colonies obtained

From: Initial in vitro screening approach to investigate the potential health and environmental hazards of Envirox™ – a nanoparticulate cerium oxide diesel fuel additive

Experiment 1
Substance Dose Level (μg/plate) TA100 TA1535 TA102 TA98 TA1537
   Mean ± S.D. Mean ± S.D. Mean ± S.D. Mean ± S.D. Mean ± S.D.
   (-S9) (+S9) (-S9) (+S9) (-S9) (+S9) (-S9) (+S9) (-S9) (+S9)
DMSO 100 μl 83 ± 7 64 ± 5 40 ± 2 12 ± 2 309 ± 24 333 ± 29 21 ± 5 26 ± 4 10 ± 2 17 ± 3
Cerium Oxide Non-nano 50 85 ± 12 73 ± 11 37 ± 5 13 ± 1 333 ± 28 361 ± 29 19 ± 4 29 ± 2 12 ± 2 19 ± 6
  150 96 ± 7 70 ± 9 34 ± 3 11 ± 2 341 ± 21 359 ± 7 19 ± 3 29 ± 3 13 ± 3 18 ± 3
  500 80 ± 12 76 ± 10 35 ± 7 11 ± 2 345 ± 9 367 ± 11 22 ± 7 29 ± 6 13 ± 3 20 ± 4
  1500 69 ± 10 75 ± 11 34 ± 2 13 ± 6 338 ± 10 350 ± 26 16 ± 2 25 ± 3 12 ± 5 21 ± 5
  5000 84 ± 7 73 ± 9 36 ± 3 10 ± 2 313 ± 21 354 ± 14 16 ± 4 31 ± 4 11 ± 1 22 ± 1