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Table 5 Results of bacterial gene point mutation assay. Cerium oxide – non-nanoparticulate. Summary of mean revertant colonies obtained

From: Initial in vitro screening approach to investigate the potential health and environmental hazards of Envirox™ – a nanoparticulate cerium oxide diesel fuel additive

Experiment 2
Substance Dose Level (μg/plate) TA100 TA1535 TA102 TA98 TA1537
   Mean ± S.D. Mean ± S.D. Mean ± S.D. Mean ± S.D. Mean ± S.D.
   (-S9) (+S9) (-S9) (+S9) (-S9) (+S9) (-S9) (+S9) (-S9) (+S9)
DMSO 100 μl 93 ± 16 105 ± 13 27 ± 7 9 ± 1 345 ± 17 374 ± 13 20 ± 3 27 ± 7 8 ± 3 13 ± 4
Cerium Oxide Non-nano 50 87 ± 10 115 ± 10 32 ± 2 11 ± 7 349 ± 42 352 ± 31 16 ± 7 23 ± 2 15 ± 4 19 ± 4
  150 95 ± 4 91 ± 8 28 ± 7 14 ± 2 343 ± 20 397 ± 21 20 ± 3 23 ± 2 8 ± 4 19 ± 5
  500 94 ± 13 89 ± 4 37 ± 5 9 ± 1 349 ± 27 364 ± 23 18 ± 2 29 ± 3 9 ± 1 17 ± 3
  1500 82 ± 2 99 ± 2 33 ± 12 9 ± 3 351 ± 22 380 ± 10 17 ± 2 28 ± 4 8 ± 4 21 ± 6
  5000 107 ± 2 97 ± 13 26 ± 4 10 ± 2 350 ± 49 382 ± 21 18 ± 4 23 ± 6 15 ± 5 19 ± 3
  1. S.D. Standard deviation