Skip to main content

Table 7 Results of bacterial gene point mutation assay. Cerium oxide - nanoparticulate. Summary of mean revertant colonies obtained

From: Initial in vitro screening approach to investigate the potential health and environmental hazards of Envirox™ – a nanoparticulate cerium oxide diesel fuel additive

Experiment 2
Substance Dose Level (μg/plate) TA100 TA1535 TA102 TA98 TA1537
   Mean ± S.D. Mean ± S.D. Mean ± S.D. Mean ± S.D. Mean ± S.D.
   (-S9) (+S9) (-S9) (+S9) (-S9) (+S9) (-S9) (+S9) (-S9) (+S9)
DMSO 100 μl 97 ± 14 132 ± 8 28 ± 6 30 ± 11 394 ± 9 380 ± 25 21 ± 5 38 ± 7 12 ± 10 15 ± 6
Cerium Oxide Nano 50 99 ± 19 123 ± 17 32 ± 2 29 ± 5 359 ± 28 397 ± 39 21 ± 4 33 ± 10 12 ± 1 13 ± 6
  150 98 ± 20 127 ± 10 35 ± 6 40 ± 6 361 ± 32 391 ± 32 22 ± 4 32 ± 2 14 ± 7 12 ± 4
  500 84 ± 6 126 ± 11 35 ± 11 32 ± 4 382 ± 29 350 ± 7 21 ± 4 32 ± 5 14 ± 4 16 ± 4
  1500 (F) 92 ± 8 133 ± 7 36 ± 8 36 ± 7 361 ± 43 313 ± 29 19 ± 5 37 ± 4 9 ± 3 12 ± 3
  5000 (F+P+M) 95 ± 3 121 ± 22 28 ± 5 29 ± 3 371 ± 24 353 ± 36 19 ± 3 26 ± 3 9 ± 1 17 ± 2
  1. S.D. Standard deviation
  2. F Film
  3. P Precipitate
  4. M Manual Count