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Table 7 Results of bacterial gene point mutation assay. Cerium oxide - nanoparticulate. Summary of mean revertant colonies obtained

From: Initial in vitro screening approach to investigate the potential health and environmental hazards of Envirox™ – a nanoparticulate cerium oxide diesel fuel additive

Experiment 2

Substance

Dose Level (μg/plate)

TA100

TA1535

TA102

TA98

TA1537

  

Mean ± S.D.

Mean ± S.D.

Mean ± S.D.

Mean ± S.D.

Mean ± S.D.

  

(-S9)

(+S9)

(-S9)

(+S9)

(-S9)

(+S9)

(-S9)

(+S9)

(-S9)

(+S9)

DMSO

100 μl

97 ± 14

132 ± 8

28 ± 6

30 ± 11

394 ± 9

380 ± 25

21 ± 5

38 ± 7

12 ± 10

15 ± 6

Cerium Oxide Nano

50

99 ± 19

123 ± 17

32 ± 2

29 ± 5

359 ± 28

397 ± 39

21 ± 4

33 ± 10

12 ± 1

13 ± 6

 

150

98 ± 20

127 ± 10

35 ± 6

40 ± 6

361 ± 32

391 ± 32

22 ± 4

32 ± 2

14 ± 7

12 ± 4

 

500

84 ± 6

126 ± 11

35 ± 11

32 ± 4

382 ± 29

350 ± 7

21 ± 4

32 ± 5

14 ± 4

16 ± 4

 

1500 (F)

92 ± 8

133 ± 7

36 ± 8

36 ± 7

361 ± 43

313 ± 29

19 ± 5

37 ± 4

9 ± 3

12 ± 3

 

5000 (F+P+M)

95 ± 3

121 ± 22

28 ± 5

29 ± 3

371 ± 24

353 ± 36

19 ± 3

26 ± 3

9 ± 1

17 ± 2

  1. S.D. Standard deviation
  2. F Film
  3. P Precipitate
  4. M Manual Count