Table 2 Profiles of experimental animals used for intravital studies.
From: Nanoparticle inhalation augments particle-dependent systemic microvascular dysfunction
| Â | Exposure Parameters | Â | Â | Â | Â | |
|---|---|---|---|---|---|---|
TiO 2 Dose/Group | Aerosol Concentration (mg/m 3 ) | Duration (min) | N | Age (days) | Weight (grams) | Mean Arterial Pressure (mm Hg) |
Sham Control | 0 | 240 | 4 | 43 ± 1 | 206 ± 11 | 98 ± 9 |
38 μg Ultrafine | 10 | 720 | 3 | 46 ± 3 * | 228 ± 29 | 98 ± 6 |
19 μg Ultrafine | 12 | 240 | 5 | 40 ± 1 | 188 ± 9 | 95 ± 4 |
10 μg Ultrafine | 6 | 240 | 4 | 42 ± 1 | 224 ± 7 | 103 ± 2 |
10 μg Ultrafine | 3 | 480 | 5 | 41 ± 1 | 202 ± 7 | 102 ± 10 |
10 μg Ultrafine | 12 | 120 | 5 | 42 ± 1 | 217 ± 6 | 107 ± 7 |
6 μg Ultrafine | 3 | 240 | 3 | 42 ± 1 | 216 ± 9 | 93 ± 7 |
4 μg Ultrafine | 1.5 | 240 | 3 | 42 ± 1 | 207 ± 8 | 96 ± 7 |
90 μg Fine | 15 | 480 | 4 | 42 ± 1 | 233 ± 4 | 97 ± 2 |
67 μg Fine | 16 | 300 | 4 | 41 ± 1 | 214 ± 11 | 96 ± 3 |
36 μg Fine | 12 | 240 | 4 | 41 ± 1 | 213 ± 6 | 100 ± 4 |
20 μg Fine | 6 | 240 | 3 | 42 ± 1 | 209 ± 8 | 101 ± 3 |
8 μg Fine | 3 | 240 | 5 | 42 ± 1 | 233 ± 9 | 106 ± 6 |