Mouse Strain
|
n
|
Exposure
|
%Albumin§
|
%LDH§
|
%Lymphocytes||
|
%PMN||
|
---|
A/J
|
7
|
GMA-MS
|
90 ± 3
|
156 ± 10*‡
|
0.64 ± 0.16 (0 ± 0)
|
12 ± 1.2*‡ (0 ± 0)
|
C57BL/6J
|
7
|
GMA-MS
|
105 ± 3
|
132 ± 3*
|
0.54 ± 0.13 (0.14 ± 0.07)
|
0.72 ± 0.3 (0.05 ± 0.05)
|
A/J
|
6
|
GMA-SS
|
115 ± 6
|
216 ± 16* †‡
|
0.86 ± 0.18* (0 ± 0)
|
20 ± 1.2*†‡ (0 ± 0)
|
C57BL/6J
|
7
|
GMA-SS
|
113 ± 4
|
148 ± 8*
|
0.8 ± 0.17 * (0.14 ± 0.07)
|
1.3 ± 0.8 (0.05 ± 0.05)
|
A/J
|
7
|
MMA-SS
|
145 ± 11*
|
144 ± 17*
|
1.8 ± 0.5* (0.1 ± 0.06)
|
12 ± 1.0*†‡ (0.1 ± 0.1)
|
C57BL/6J
|
7
|
MMA-SS
|
115 ± 8
|
130 ± 5*†
|
1.0 ± 0.36* (0 ± 0)
|
1.6 ± 0.1*† (0.07 ± 0.07)
|
A/J
|
5
|
S-Cr
|
137 ± 12*
|
111 ± 13
|
2.2 ± 0.46* (0.1 ± 0.06)
|
5.6 ± 0.6*‡ (0.1 ± 0.1)
|
C57BL/6J
|
7
|
S-Cr
|
124 ± 8*
|
111 ± 7
|
0.44 ± 0.23 (0 ± 0)
|
0.22 ± 0.2 (0.07 ± 0.07)
|
- *Significantly different from corresponding sham; † Between exposed groups of the same mouse strain; ‡Between mouse strains of the same exposure group (p < 0.05)
- §LDH and albumin data are represented as % corresponding sham. ||Percentage from a differential cell count of > 300 cells with the corresponding sham % in parentheses.
- Note. Data are means ± SE. Statistical comparisons were MMA-SS and S-Cr or GMA-MS and GMA-SS. Abbreviations are GMA-MS-gas metal arc-mild steel, GMA-SS-gas metal arc stainless steel, or MMA-SS-manual metal arc stainless steel welding fume; S-Cr-soluble chromium VI; LDH-lactate dehydrogenase; PMN-polymorphonuclear leukocytes