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Table 2 Bronchoalveolar lavage parameters 7 days post-exposure

From: Pulmonary inflammation and tumor induction in lung tumor susceptible A/J and resistant C57BL/6J mice exposed to welding fume

Mouse Strain n Exposure %Albumin§ %LDH§ %Lymphocytes|| %PMN||
A/J 7 GMA-MS 90 ± 3 156 ± 10* 0.64 ± 0.16 (0 ± 0) 12 ± 1.2* (0 ± 0)
C57BL/6J 7 GMA-MS 105 ± 3 132 ± 3* 0.54 ± 0.13 (0.14 ± 0.07) 0.72 ± 0.3 (0.05 ± 0.05)
A/J 6 GMA-SS 115 ± 6 216 ± 16* †‡ 0.86 ± 0.18* (0 ± 0) 20 ± 1.2*†‡ (0 ± 0)
C57BL/6J 7 GMA-SS 113 ± 4 148 ± 8* 0.8 ± 0.17 * (0.14 ± 0.07) 1.3 ± 0.8 (0.05 ± 0.05)
A/J 7 MMA-SS 145 ± 11* 144 ± 17* 1.8 ± 0.5* (0.1 ± 0.06) 12 ± 1.0*†‡ (0.1 ± 0.1)
C57BL/6J 7 MMA-SS 115 ± 8 130 ± 5* 1.0 ± 0.36* (0 ± 0) 1.6 ± 0.1* (0.07 ± 0.07)
A/J 5 S-Cr 137 ± 12* 111 ± 13 2.2 ± 0.46* (0.1 ± 0.06) 5.6 ± 0.6* (0.1 ± 0.1)
C57BL/6J 7 S-Cr 124 ± 8* 111 ± 7 0.44 ± 0.23 (0 ± 0) 0.22 ± 0.2 (0.07 ± 0.07)
  1. *Significantly different from corresponding sham; Between exposed groups of the same mouse strain; Between mouse strains of the same exposure group (p < 0.05)
  2. §LDH and albumin data are represented as % corresponding sham. ||Percentage from a differential cell count of > 300 cells with the corresponding sham % in parentheses.
  3. Note. Data are means ± SE. Statistical comparisons were MMA-SS and S-Cr or GMA-MS and GMA-SS. Abbreviations are GMA-MS-gas metal arc-mild steel, GMA-SS-gas metal arc stainless steel, or MMA-SS-manual metal arc stainless steel welding fume; S-Cr-soluble chromium VI; LDH-lactate dehydrogenase; PMN-polymorphonuclear leukocytes