Exposure to ambient concentrations of particulate air pollution does not influence vascular function or inflammatory pathways in young healthy individuals

Table 4 Correlation coefficients for all day correlations among biomarkers and microvascular function score^a

	Haemoglobin	RBC	Fibrinogen	Platelets	II+VII+X	CRP	IL-6	TNF	PLAAS^c	AAPH^d	BMI^e
MVF score^b	-0.018	-0.009	-0.059	0.014	-0.042	-0.114	0.008	-0.113	-0.142	0.131	0.015
Haemoglobin		0.765	-0.116	-0.320	0.226	-0.253	-0.042	0.098	-0.060	0.327	0.317
Red blood cells (RBC)			-0.062	-0.157	-0.021	-0.207	-0.007	0.050	-0.074	0.346	0.190
Fibrinogen				0.253	-0.389	0.355	0.170	0.016	0.035	-0.110	0.286
Platelets					-0.458	0.037	-0.100	-0.103	0.017	-0.298	0.209
Coagulation factor II+VII+X						-0.308	-0.005	-0.002	-0.010	0.096	-0.117
C-reactive protein (CRP)							0.228	0.222	0.106	0.278	-0.057
Interleukin (IL-6)								0.118	0.131	0.063	-0.022
Tumour necrosis factor (TNF)-α^g									0.032	-0.135	-0.183
PLAAS^c										-0.096	0.072
AAPH^d											0.033

^aCorrelations were made on raw data. Numbers in bold depict statistically significant values (p < 0.05)
^bMVF, microvascular function score was positively correlated with platelets (not significant, NS), IL6 (NS), BMI(NS) and AAPH (borderline significant, P = 0.05) and negatively correlated with PLAAS (significant) and the remaining biomarkers (NS)
^c2-aminoapidic semialdehyde in plasma proteins
^dSusceptibility to lipoprotein oxidation in plasma was measured as lagtime (min) of ex vivo oxidation with AAPH (2,2'-azobis(2-aminopropane)dihydrochloride)
^eBody mass index

ISSN: 1743-8977