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Table 4 Increase in lymph node burden from 7 to 42 days post-exposure

From: Pulmonary response to intratracheal instillation of ultrafine versus fine titanium dioxide: role of particle surface area

Particle Percent increase
UFTiO2 246 ± 118%
FTiO2 134 ± 2%
  1. Values are for medium dose exposures (0.52 mg/rat vs 10.7 mg/rat for UFTiO2 and FTiO2, respectively, i.e., a surface area dose of 0.06 cm2 particles/cm2 alveolar epithelial surface). Values are means ± SE of at least 4 experiments.