Skip to main content
Figure 4 | Particle and Fibre Toxicology

Figure 4

From: DNA damage and cytotoxicity in type II lung epithelial (A549) cell cultures after exposure to diesel exhaust and urban street particles

Figure 4

DNA damage measured by the comet assay in A549 cells exposed to SRM2975 and SRM1650 for 3, 24 or 48 hours. (A) SB, SRM2975, (B) FPG sites, SRM2975, (C) SB, SRM1650 and (D) FPG sites, SRM1650. Mean ± SEM, n = 9. * Dose where all exposure times are statistically significant compared to control (p < 0.01, ANOVA, except for 3 hours exposure to 100 μg/ml where SRM1650 is tested with Kruskal-Wallis test, p < 0.05). # Dose where a single time point is statistically significant compared to the respective control (ANOVA): (A) SRM2975, SB, 2.5 μg/ml, 48 h, p < 0.05, (C) SRM1650, SB, 2.5 μg/ml, 3 h, p < 0.05 and SRM1650, SB, 25 μg/ml, 48 h, p < 0.01, (D) SRM1650, FPG, 2.5 μg/ml, 3 h, p < 0.05 and SRM1650, FPG, 25 μg/ml, 24 h, p < 0.05.

Back to article page