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Table 2 Potency difference between UFCB and FCB when analyzed on a mass vs. surface area.

From: Surface area of particle administered versus mass in determining the pulmonary toxicity of ultrafine and fine carbon black: comparison to ultrafine titanium dioxide

Parameter Dose Metric 1 Day 7 Days 42 Days
PMN (106)     
  Mass 65 65 65
  Surface Area 2 1.5 1.6
LDH (U/l)     
  Mass 65 65 65
  Surface Area 1.5 2 1.8
Albumin     
  Mass 65 65 65
  Surface Area 1.5 2 2
TNF-α (pg/ml)     
  Mass 130 130 130
  Surface Area 1.4 1.5 1.5
MIP-2 (pg/ml)     
  Mass 130 130 130
  Surface Area 1.4 1.7 1.3
IL-1β (pg/ml)     
  Mass 130 130 130
  Surface Area 2.4 2.6 2.3
Zym. Stim. Chemi.     
  Mass 130 130 130
  Surface Area 1.5 1.75 1.2
NO Dep. Chemi.     
  Mass 68 130 130
  Surface Area 1.5 2.5 3
  1. Comparison of UFCB and FCB potency differences.
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Particle and Fibre Toxicology

ISSN: 1743-8977

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