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Table 2 Potency difference between UFCB and FCB when analyzed on a mass vs. surface area.

From: Surface area of particle administered versus mass in determining the pulmonary toxicity of ultrafine and fine carbon black: comparison to ultrafine titanium dioxide

Parameter

Dose Metric

1 Day

7 Days

42 Days

PMN (106)

    
 

Mass

65

65

65

 

Surface Area

2

1.5

1.6

LDH (U/l)

    
 

Mass

65

65

65

 

Surface Area

1.5

2

1.8

Albumin

    
 

Mass

65

65

65

 

Surface Area

1.5

2

2

TNF-α (pg/ml)

    
 

Mass

130

130

130

 

Surface Area

1.4

1.5

1.5

MIP-2 (pg/ml)

    
 

Mass

130

130

130

 

Surface Area

1.4

1.7

1.3

IL-1β (pg/ml)

    
 

Mass

130

130

130

 

Surface Area

2.4

2.6

2.3

Zym. Stim. Chemi.

    
 

Mass

130

130

130

 

Surface Area

1.5

1.75

1.2

NO Dep. Chemi.

    
 

Mass

68

130

130

 

Surface Area

1.5

2.5

3

  1. Comparison of UFCB and FCB potency differences.
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Particle and Fibre Toxicology

ISSN: 1743-8977

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