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Figure 2 | Particle and Fibre Toxicology

Figure 2

From: Ultrafine carbon particles down-regulate CYP1B1 expression in human monocytes

Figure 2

Particle induced down-regulation of CYP1B1 is not due to contaminant LPS. CD14++ monocytes remained untreated (none) or were stimulated with LPS (10 ng/ml) and ultrafine P90 (32 μg/ml) each with and without 15 min PolymyxinB preincubation to suppress the LPS effect. After incubation for 3 h cells were lysed and mRNA levels were determined by RT-PCR (n = 6 incubations from different donors, mean ± S.D.; * p < 0.05 compared to untreated cells).

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