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Figure 1 | Particle and Fibre Toxicology

Figure 1

From: Pathway focused protein profiling indicates differential function for IL-1B, -18 and VEGF during initiation and resolution of lung inflammation evoked by carbon nanoparticle exposure in mice

Figure 1

Bronchoalveolar lavage fluid (BAL) cell differentials and protein concentration. a) Dose dependent influx and time dependent resolution of polymorphonuclear leukocytes (PMN) in the BAL following intratracheal (i.t.) instillation of carbon nanoparticles (CNP) particles in the C3H/HeJ (C3) mice. (n = 7 animals/experimental group). b) Total cell count in the BAL of C3 mice following i.t. instillation of CNP particles. c) Total protein concentration in the BAL of C3 mice showing a dose dependent increase and time dependent decrease following i.t instillation of CNP. (**) Significantly different with respect to (w.r.t) both sham control and 5 μg exposed; (†) significantly different w.r.t 20 μg exposed at day 1; (††) significantly different w.r.t 20 μg at day 1, 5 μg and scham control.

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Particle and Fibre Toxicology

ISSN: 1743-8977

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