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Figure 2 | Particle and Fibre Toxicology

Figure 2

From: Pathway focused protein profiling indicates differential function for IL-1B, -18 and VEGF during initiation and resolution of lung inflammation evoked by carbon nanoparticle exposure in mice

Figure 2

Heatmap representation of protein concentration levels in lung homogenate and bronchoalveolar lavage (BAL) following intratracheal instillation of carbon nanoparticles (CNP) in C3H/HeJ (C3) mice. Data shown are normalized (highest value is set to "1") for (a) dose and time response for the lung; and (b) dose and time response for the BAL, respectively. Red color indicates increasing concentration levels and official protein symbols and the fold inductions for each protein at different dose and time are shown. A schematic graphical representation of the markers categorized as category 1A, 1B, 2A, and 2B in the lung as calculated by the ratio [percent day 7/day 1] is shown and are explained in the results section.

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Particle and Fibre Toxicology

ISSN: 1743-8977

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